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Congenital Adrenal Hyperplasia: Exam Prep
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Module 1
Adrenal Steroidogenesis: Pathway and Principles
Adrenal Cortex Zones & Hormones
Recall the three zones of the adrenal cortex and the primary class of hormone synthesized in each.
2
Steroidogenesis Pathway: Cholesterol to Steroid Hormones
Sketch the simplified steroidogenesis pathway, showing the flow from cholesterol to mineralocorticoids, glucocorticoids, and androgens.
3
Locating Key Enzymes in the Steroid Synthesis Pathway
Pinpoint the locations of the three key enzymes (17α-hydroxylase, 21-hydroxylase, 11β-hydroxylase) within the pathway.
4
Enzyme Block: Precursor Accumulation & Product Deficiency
State the general principle of an enzyme block: accumulation of precursors and deficiency of downstream products.
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