Diagnosis and Management Strategy

Outline the diagnostic pathway for acromegaly, from initial screening with IGF-1 to confirmation with OGTT and localization with MRI.

Describe the primary treatment goals and the role of transsphenoidal surgery as first-line therapy.

Compare the indications and roles for the main classes of medical therapy in acromegaly: somatostatin receptor ligands, GH receptor antagonists, and dopamine agonists.

Define the criteria for disease remission and outline the principles of long-term monitoring for treated patients.